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Human Hepatic Uptake Transporter

Human Hepatic Uptake Transporter. Uptake transporters, such as organic anion transporters (oats and oatps), mediate the uptake of conjugates into the liver and kidney, while efflux transporters, such as. A novel human hepatic organic anion transporting polypeptide (oatp2) a novel human organic transporter, oatp2, has been identified that transports taurocholic acid, the adrenal androgen.

Selected human transport proteins for drugs and endogenous
Selected human transport proteins for drugs and endogenous from www.researchgate.net

Organic anion transporting polypeptide (oatp) 1b1, oatp1b3, and oatp2b1 (encoded by slco1b1, slco1b3, slco2b1) mediate the hepatic uptake of endogenous. Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter slc21a6*. A novel human hepatic organic anion transporting polypeptide (oatp2) a novel human organic transporter, oatp2, has been identified that transports taurocholic acid, the adrenal androgen.

Hepatic Uptake Of Bilirubin And Its Conjugates By The Human Organic Anion Transporter Slc21A6*.


Uptake transporters, such as organic anion transporters (oats and oatps), mediate the uptake of conjugates into the liver and kidney, while efflux transporters, such as. In humans, six major hepatic uptake transporters belonging to solute carrier (slc) superfamily, namely, organic anion transporting polypeptide 1b1 (oatp1b1/slco1b1), oatp1b3. Organic anion transporting polypeptide (oatp) 1b1, oatp1b3, and oatp2b1 (encoded by slco1b1, slco1b3, slco2b1) mediate the hepatic uptake of endogenous.

Bilirubin, The End Product Of Heme Catabolism, Is Taken Up From The Blood.


A novel human hepatic organic anion transporting polypeptide (oatp2) a novel human organic transporter, oatp2, has been identified that transports taurocholic acid, the adrenal androgen.

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